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Characteristics of open‐ and closed‐loop smooth pursuit responses among obsessive‐compulsive disorder, schizophrenia, and nonpsychiatric individuals
Author(s) -
FARBER ROBERT H.,
CLEMENTZ BRETT A.,
SWERDLOW NEAL R.
Publication year - 1997
Publication title -
psychophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.661
H-Index - 156
eISSN - 1469-8986
pISSN - 0048-5772
DOI - 10.1111/j.1469-8986.1997.tb02126.x
Subject(s) - smooth pursuit , psychology , schizophrenia (object oriented programming) , obsessive compulsive , interval (graph theory) , task (project management) , audiology , developmental psychology , psychiatry , neuroscience , eye movement , medicine , mathematics , management , combinatorics , economics
Twenty obsessive‐compulsive disorder patients and comparison samples of 20 schizophrenia and 20 nonpsychiatric individuals were presented with (a) a step‐ramp task designed to measure smooth pursuit initiation and (b) a regular ramp task designed to measure steady‐stale tracking performance. Obsessive‐compulsive disorder and non‐psychiatric individuals had statistically similar pursuit reaction time and average eye accelerations during the open‐loop interval. They also had similar closed‐loop performance. Schizophrenia patients, however, had delayed pursuit reaction times and reduced eye acceleration during the last 60 ms of the open‐loop interval. These findings suggest that brain regions supporting smooth pursuit performance are unimpaired among obsessive‐compulsive disorder patients. Furthermore, the deficits found in the schizophrenia patients replicate and extend the results of previous smooth pursuit studies.