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Assessment of baroreflex control from beat‐to‐beat blood pressure and heart rate changes: A validation study
Author(s) -
WATKINS LANA L.,
FAINMAN CLAUDIA,
DIMSDALE JOEL,
ZIEGLER MICHAEL G.
Publication year - 1995
Publication title -
psychophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.661
H-Index - 156
eISSN - 1469-8986
pISSN - 0048-5772
DOI - 10.1111/j.1469-8986.1995.tb01224.x
Subject(s) - baroreflex , blood pressure , heart rate , reflex , anesthesia , pulse pressure , cardiology , beat (acoustics) , pulse rate , baroreceptor , pulse (music) , medicine , psychology , physics , detector , optics , acoustics
In this study, we tested the validity of a new method designed to estimate baroreflex control of heart rate from spontaneous changes in systolic pressure and pulse interval. This method was compared with a conventional method of assessing baroreflex control through measuring reflex adjustments in pulse interval associated with pharmacological manipulations of blood pressure. The estimates of baroreflex control derived from the two methods were signficantly correlated; however, only the estimate derived using pharmacological changes in pressure detected significant impairment of baroreflex control in patients with damage to baroafferents produced by radiation for oropharyngeal cancer. Analysis of spontaneous changes in pressure and pulse interval therefore provide a meaningful estimate of baroreflex control of heart rate that is, however, less sensitive than estimates obtained using pharmacological manipulations in pressure.