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Behaviour in children with neurofibromatosis type 1: cognition, executive function, attention, emotion, and social competence
Author(s) -
LEHTONEN ANNUKKA,
HOWIE EMMA,
TRUMP DOROTHY,
HUSON SUSAN M
Publication year - 2013
Publication title -
developmental medicine and child neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.658
H-Index - 143
eISSN - 1469-8749
pISSN - 0012-1622
DOI - 10.1111/j.1469-8749.2012.04399.x
Subject(s) - psycinfo , psychology , medline , cognition , competence (human resources) , neurofibromatosis , developmental psychology , narrative review , social competence , executive functions , social skills , working memory , clinical psychology , cognitive psychology , medicine , psychiatry , psychotherapist , social psychology , social change , political science , law , economics , radiology , economic growth
Aim This systematic review aimed to pull together the findings from research into behavioural systems and attention in children with neurofibromatosis type 1 (NF1) and to identify areas that need further study. Method Relevant papers were identified through searches of electronic databases (MEDLINE, PsycINFO, EMBASE) and manual searches through reference lists. In total, 5746 articles were identified and 57 met the inclusion criteria. The data were synthesized using the narrative approach, as the studies varied considerably in terms of participants and measures. Results The results of the review showed that intelligence, academic skills, visuospatial skills, social competence, and attention are impaired in children with NF1. Evidence of deficits in memory, motor functioning, language, and executive functions was less clear. Interpretation Research has made marked progress in outlining the behavioural phenotype of NF1. However, although the general areas of impairment are becoming better known, the exact nature of the impairment is still not understood in many areas of behaviour. Care needs to be taken with the way in which behavioural constructs are defined and measured, and the variability of problems in NF1 is a particular challenge. Nevertheless, research is steadily moving towards comprehensive understanding of behaviour in children with NF1.