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Mechanical ventilation for respiratory failure in children with severe neurological impairment: is it futile medical treatment?
Author(s) -
VAN GESTEL JOSEPHUS PJ,
ROBROCH AFKE H,
BOLLEN CASPER W,
VAN DER ENT CORNELIS K,
VAN VUGHT ADRIANUS J
Publication year - 2010
Publication title -
developmental medicine and child neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.658
H-Index - 143
eISSN - 1469-8749
pISSN - 0012-1622
DOI - 10.1111/j.1469-8749.2009.03582.x
Subject(s) - medicine , mechanical ventilation , respiratory failure , pediatrics , intensive care unit , ventilation (architecture) , intensive care medicine , surgery , anesthesia , mechanical engineering , engineering
Aim To assess outcome for children with severe neurological impairment receiving invasive mechanical ventilation for respiratory failure. Method Medical charts for all such children treated in our intensive care unit (ICU) between January 2003 and July 2008 were reviewed. Outcomes were compared with those for children with moderate neurological impairment. Results Twenty‐two children with severe neurological impairment were included (nine females, 13 males; median age 7y 10mo; range 4mo–17y). The median duration of mechanical ventilation was 16 days. Six children had an uneventful 1‐year survival, the others required reintubation or readmission to the ICU, or died. Eleven children were still alive 1 year after discharge from the ICU. Nine patients died of respiratory failure. None of the children in the severe group died of a heart defect. Eleven children with moderate neurological impairment were included (eight females, three males; median age 1y 1mo, range 4mo–13y). Four children had an uneventful 1‐year survival. Eight children were still alive 1 year after discharge from the ICU. Two of the three non‐survivors died of their heart defects. Interpretation Mechanical ventilation for respiratory failure in children with severe neurological impairment is complex and associated with limited survival. However, it cannot be regarded as futile medical treatment. Further studies are urgently needed for the rational guidance of clinical decision‐making.