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Stimulant medication in 47,XYY syndrome: a report of two cases
Author(s) -
Ruud Anne,
Arnesen Peter,
Stray Liv Larsen,
Vildalen Stéphane,
Vesterhus Per
Publication year - 2005
Publication title -
developmental medicine and child neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.658
H-Index - 143
eISSN - 1469-8749
pISSN - 0012-1622
DOI - 10.1111/j.1469-8749.2005.tb01192.x
Subject(s) - methylphenidate , stimulant , psychology , neuropsychology , attention deficit hyperactivity disorder , cognition , psychiatry , pediatrics , clinical psychology , medicine
In two males, 11 and 12 years of age, referred for attention‐deficit‐hyperactivity disorder (ADHD), 47,XYY syndrome was diagnosed. A team that included a neuropsychologist, a physiotherapist, and a physician examined them. Stature (patients were above 97.5% height for age), muscle consistency, and tremor indicated chromosome analysis. Psychological tests results did not fully fit the ADHD diagnosis. On the basis of our clinical observation we felt that stimulant medication was indicated. Administration of methylphenidate led to improved motor and cognitive functions as well as social adaptation in both patients. We suggest that this treatment might well be considered in clinically similar patients with XYY sex chromosomes; we further suggest that learning problems in such individuals may be related to ADHD.