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Children with ADHD and motor dysfunction compared with children with ADHD only
Author(s) -
Tervo Raymond C,
Azuma Scott,
Fogas Bruce,
Fiechtner Helen
Publication year - 2002
Publication title -
developmental medicine and child neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.658
H-Index - 143
eISSN - 1469-8749
pISSN - 0012-1622
DOI - 10.1111/j.1469-8749.2002.tb00832.x
Subject(s) - methylphenidate , placebo , attention deficit hyperactivity disorder , psychology , crossover study , attention deficit , pediatrics , medicine , randomized controlled trial , psychiatry , alternative medicine , pathology
The purpose of this study was to identify group differences in children with attention‐deficit‐hyperactivity disorder and motor dysfunction (ADHD‐MD) and ADHD only, and to evaluate the medication responsiveness of ADHD‐MD. Sixty‐three children (49 males and 14 females; mean age 9 years 10 months, SD 2 years 10 months) underwent a triple blind, placebo‐controlled crossover study evaluating two dose levels of methylphenidate (0.3 mg/kg and 0.05 mg/kg, twice daily) and placebo. Forty‐nine trials were completed. Nineteen were children with ADHD‐MD, 44 had ADHD only. Behavior and functioning were assessed at home and at school. Treatment effects were assessed using the Abbreviated Symptom Questionnaire for Parents and Teachers. Children with ADHD‐MD were more likely to have severe ADHD‐combined type and other neurodevelopmental and behavioral problems. Both groups of children had a linear dose response to medication (placebo, low, high) and there was no evidence of a group by dose interaction or an overall group effect at home or school. The lack of group effect suggests that these children responded to medication like the other subgroups.