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Rasmussen's encephalitis followed by lupus erythematosus
Author(s) -
Lascelles K,
Dean A F,
Robinson Richard O
Publication year - 2002
Publication title -
developmental medicine and child neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.658
H-Index - 143
eISSN - 1469-8749
pISSN - 0012-1622
DOI - 10.1111/j.1469-8749.2002.tb00331.x
Subject(s) - medicine , encephalitis , hemispherectomy , rash , pediatrics , epilepsy , malar rash , dermatology , immunology , psychiatry , anti nuclear antibody , virus , antibody , autoantibody
A 6‐year‐old female presented with right hemichorea, initially thought to be post‐streptococcal, which subsequently progressed to a right dystonic hemiplegia. At 7½ years she developed right focal and secondary generalized tonic‐clonic seizures. These became intractable. A brain biopsy was consistent with Rasmussen's encephalitis (RE). At 9½ years the child underwent a left hemispherectomy making a good recovery with resolution of seizures. At 12 years she presented with recurrent episodes of abdominal pain, fever, and malar rash with serological evidence of systemic lupus erythematosus (SLE). A possible link between RE and SLE is discussed.