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Carbamazepine hypersensitivity and the use of lymphocyte proliferation responses
Author(s) -
Brown K L,
Henderson D C,
Nadel S,
Tanveer A,
Booy R
Publication year - 1999
Publication title -
developmental medicine and child neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.658
H-Index - 143
eISSN - 1469-8749
pISSN - 0012-1622
DOI - 10.1111/j.1469-8749.1999.tb00596.x
Subject(s) - carbamazepine , medicine , hypersensitivity reaction , monocyte , lymphocyte , peripheral blood , immunology , seizure disorders , delayed hypersensitivity , pharmacology , epilepsy , immune system , psychiatry
This report describes a case of multisystem failure in a 5‐year‐old boy who was being treated with carbamazepine for a seizure disorder. Carbamazepine hypersensitivity was diagnosed from the combination of the clinical constellation and the results of the patient's peripheral blood monocyte proliferation responses to both carbamazepine and a panel of other medications.