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The absorption of antibody by the duodenum and jejunum in young rats
Author(s) -
Morris B.,
Begley D.
Publication year - 1970
Publication title -
journal of zoology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.915
H-Index - 96
eISSN - 1469-7998
pISSN - 0952-8369
DOI - 10.1111/j.1469-7998.1970.tb01279.x
Subject(s) - jejunum , duodenum , biology , antibody , absorption (acoustics) , ileum , saline , immune system , small intestine , immunity , endocrinology , medicine , physiology , immunology , materials science , composite material
Experiments were performed to test the capacity of parts of the small intestine of rats aged27–29 days to absorb homologous antibody and transmit it to the circulation. No antibody absorption occurs after the oral administration of immune serum to rats of this age, for the postnatal transfer of immunity normally terminates at about20–21 days. Antibody is readily absorbed and transmitted to the circulation from homologous immune serum introduced into the duodenum of27–28 day animals, after removal of the duodenal contents by flushing out with warm saline. Absorption and transmission occurs in some animals even if the duodenal contents are not previously removed. The animals used in these experiments were left with their mothers until shortly before the operation. No transmission of antibody occurred when comparable experiments were performed on young rats aged27–28 days that had been weaned at the usual age of20–21 days. Similar experiments were performed on the first segment of the jejunum. The results obtained are discussed in relation to the pinocytic activity of the epithelial components of the duodenum‐jejunum.