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Mammalian brainstem chemosensitive neurones: linking them to respiration in vitro
Author(s) -
Ballantyne D.,
Scheid P.
Publication year - 2000
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1111/j.1469-7793.2000.00567.x
Subject(s) - brainstem , medulla , respiration , hypercapnia , neuroscience , in vitro , medulla oblongata , respiratory system , biology , chemistry , anatomy , central nervous system , biochemistry
Neurones which are excited by CO 2 or H + are present in a number of brainstem structures in addition to the ventrolateral region of the medulla, the site at which the respiratory response to hypercapnia is traditionally believed to originate. In this review we examine recent work concerned with establishing the relationship between these chemosensitive neurones and respiration, the emphasis being placed on the use for this purpose of in vitro preparations of the mammalian brainstem.