Premium
How to build and rebuild a lens
Author(s) -
Tsonis Panagiotis A.
Publication year - 2006
Publication title -
journal of anatomy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.932
H-Index - 118
eISSN - 1469-7580
pISSN - 0021-8782
DOI - 10.1111/j.1469-7580.2006.00634.x
Subject(s) - transdifferentiation , lens (geology) , regeneration (biology) , biology , through the lens metering , computer science , stem cell , microbiology and biotechnology , computational biology , evolutionary biology , anatomy , paleontology
Evolution has used many different strategies to build eyes and lenses. However, the genetic regulation involved seems to be quite conserved. Likewise, the regeneration of eye structures is remarkable, especially in salamanders. This review outlines the basic mechanisms of lens regeneration and its induction and the possibility of creating lenses by transdifferentiation of the pigment epithelial cells, by stem cells or by bioengineering.