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Genetically Modified Mouse Models in Studies on Cutaneous Wound Healing
Author(s) -
Scheid Annette,
Meuli Martin,
Gassmann Max,
Wenger Roland H.
Publication year - 2000
Publication title -
experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0958-0670
DOI - 10.1111/j.1469-445x.2000.02103.x
Subject(s) - wound healing , genetically modified mouse , transgene , gene transfer , knockout mouse , gene knockout , genetically modified organism , function (biology) , biology , gene , computational biology , medicine , microbiology and biotechnology , immunology , genetics
Genetically modified mice have become an invaluable tool in modern biomedical and basic research. This review provides an overview of knockout and transgenic mice studied with regard to their cutaneous wound healing properties. In addition, several gene transfer studies are briefly introduced, which have further highlighted our knowledge on individual gene function in wound healing