Premium
Icln, An Ion Channel‐Forming Protein Associated with Cell Volume Regulation
Author(s) -
Gschwentner M.,
Fürst J.,
Ritter M.,
Bazzini C.,
Wöll E.,
Dienstl A.,
Jakab M.,
König M.,
Scandella E.,
Rudzki J.,
Botta G.,
Meyer G.,
Lang F.,
Deetjen P.,
Paulmichl M.
Publication year - 1999
Publication title -
experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0958-0670
DOI - 10.1111/j.1469-445x.1999.01941.x
Subject(s) - volume (thermodynamics) , ion channel , cell , microbiology and biotechnology , chemistry , biophysics , channel (broadcasting) , biology , biochemistry , computer science , physics , receptor , quantum mechanics , computer network
SUMMARY It is not resolved whether the anionic channel involved in volume regulation after cell swelling comprises one or more subunits. Moreover, it remains to be determined which of the different proteins cloned so far, for which an involvement in cell volume regulation has been postulated, is the ideal candidate. In this review, we consider the role of the ICln protein, cloned from MDCK cells, in cell volume regulation.