Premium
Contrasting Patterns of Nuclear and mtDNA Diversity in Native American Populations
Author(s) -
Yang Ning Ning,
Mazières Stephane,
Bravi Claudio,
Ray Nicolas,
Wang Sijia,
Burley MariWyn,
Bedoya Gabriel,
Rojas Winston,
Parra Maria V.,
Molina Julio A.,
Gallo Carla,
Poletti Giovanni,
Hill Kim,
Hurtado Ana M.,
PetzlErler Maria L.,
Tsuneto Luiza T.,
Klitz William,
Barrantes Ramiro,
Llop Elena,
Rothhammer Francisco,
Labuda Damian,
Salzano Francisco M.,
Bortolini MariaCátira,
Excoffier Laurent,
Dugoujon Jean Michel,
RuizLinares Andrés
Publication year - 2010
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1111/j.1469-1809.2010.00608.x
Subject(s) - population , divergence (linguistics) , geography , evolutionary biology , autosome , effective population size , biology , ecology , genetic diversity , demography , chromosome , genetics , sociology , gene , linguistics , philosophy
Summary We report an integrated analysis of nuclear (autosomal, X‐ and Y‐chromosome) short tandem repeat (STR) data and mtDNA D‐loop sequences obtained in the same set of 22 Native populations from across the Americas. A north to south gradient of decreasing population diversity was observed, in agreement with a settlement of the Americas from the extreme northwest of the continent. This correlation is stronger with “least cost distances,” which consider the coasts as facilitators of migration. Continent‐wide estimates of population structure are highest for the Y‐chromosome and lowest for the autosomes, consistent with the effective size of the different marker systems examined. Population differentiation is highest in East South America and lowest in Meso America and the Andean region. Regional analyses suggest a deviation from mutation–drift equilibrium consistent with population expansion in Meso America and the Andes and population contraction in Northwest and East South America. These data hint at an early divergence of Andean and non‐Andean South Americans and at a contrasting demographic history for populations from these regions.