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Chromosomal mapping of a human phenol UDP‐glucuronosyltransferase, GNT1
Author(s) -
HARDING D.,
JEREMIAH S. J.,
POVEY S.,
BURCHELL B.
Publication year - 1990
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1111/j.1469-1809.1990.tb00356.x
Subject(s) - southern blot , complementary dna , gene , biology , somatic cell , microbiology and biotechnology , chromosome , genetics , dna
SUMMARY A 5' fragment of a full‐length cDNA clone encoding a human phenol UDP‐glucuronosyltransferase was used to produce a specific probe for this gene. DNA isolated from a panel of 18 human‐rodent somatic cell hybrids was analysed by Southern‐blot hybridization. The results indicate that this UDP‐glucuronosyltransferase is encoded by a single gene, designated GNT1, located on human chromosome 2.