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Cloning and chromosomal mapping of human cytochrome b 5 reductase ( DIA1 )
Author(s) -
BULL P. C.,
SHEPHARD E. A.,
POVEY S.,
SANTISTEBAN I.,
PHILLIPS I. R.
Publication year - 1988
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1111/j.1469-1809.1988.tb01105.x
Subject(s) - complementary dna , southern blot , biology , microbiology and biotechnology , genetics , gene , reductase , cytochrome b , cloning (programming) , gene mapping , chromosome , mitochondrial dna , enzyme , biochemistry , computer science , programming language
Summary We have isolated a cDNA clone that codes for human cytochrome b 5 reductase. The cDNA was used to analyse, by Southern‐blot hybridization, DNA isolated from a panel of 11 independent human‐rodent somatic cell hybrids. The results indicate that cytochrome b 5 reductase is encoded by a single gene located on human chromosome 22.