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Localization of MIC5 to the region between HPRT and G6PD on the human X chromosome
Author(s) -
HOPE By R.,
GOSS S.,
SOLOMON E.,
ROPERS H.H.,
BANTING G.,
GOODFELLOW P. N.
Publication year - 1987
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1111/j.1469-1809.1987.tb00861.x
Subject(s) - hypoxanthine guanine phosphoribosyltransferase , genetics , chromosome , biology , evolutionary biology , gene , mutant
Summary The X‐linked gene, MIC5 , encodes a human cell‐surface antigen, R1. We have assigned MIC5 to the region between HPRT and G6PD on the long arm of the X chromosome. Regional localization was based on the pattern of reactivity of the R1 monoclonal antibody with human‐rodent somatic cell hybrids which contained different fragments of the human X chromosome.