Chiasma derived genetic lengths and recombination fractions: a 46, XY, t(9; 10) (p22; q24) reciprocal translocation | Zendy

LAURIE D. A. | Zendy; PALMER R. W. | Zendy; HULTÉN M. A. | Zendy

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Chiasma derived genetic lengths and recombination fractions: a 46, XY, t(9; 10) (p22; q24) reciprocal translocation

Author(s) -

LAURIE D. A.,

PALMER R. W.,

HULTÉN M. A.

Publication year - 1985

Publication title -

annals of human genetics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.537

H-Index - 77

eISSN - 1469-1809

pISSN - 0003-4800

DOI - 10.1111/j.1469-1809.1985.tb01685.x

Subject(s) - chiasma , chromosomal translocation , karyotype , biology , centromere , chromosome , genetics , recombination , chromosomal crossover , chromosomal rearrangement , gene

Summary Chiasma distribution data on chromosomes 1, 2 and 9 from a reciprocal translocation carrier with a 46, XY, t(9; 10) (p22; q24) karyotype were used to calculate genetic distances and recombination fractions for chromosome segments corresponding to the major mitotic bands and for intervals between the centromeres and points at 10% intervals along the chromosome arms. These values were compared with those from control males with normal karyotypes. The translocation showed a marked increase in crossing‐over in one specific region of chromosome 9 and, in addition, there was evidence of interchromosomal effects in chromosomes 1 and 2.

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