Premium
Approximate linkage equilibrium between two polymorphic sites within the gene for human complement component 3
Author(s) -
DONALD J. A.,
BALL S. P.
Publication year - 1984
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1111/j.1469-1809.1984.tb01024.x
Subject(s) - linkage disequilibrium , genetics , haplotype , restriction fragment length polymorphism , biology , allele , gene , complement (music) , genotype , phenotype , complementation
Summary Haplotypes have been determined for alleles at two separate polymorphic sites within the human structural gene for complement component 3, identified as a protein polymorphism and as a restriction fragment length polymorphism by hybridization using a cloned gene probe. No evidence was found for appreciable disequilibrium between alleles at these sites, despite their very close linkage.