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Design considerations in the estimation of intraclass correlation
Author(s) -
DONNER A.,
KOVAL J. J.
Publication year - 1982
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1111/j.1469-1809.1982.tb00718.x
Subject(s) - intraclass correlation , estimator , statistics , correlation , mathematics , balance (ability) , estimation , value (mathematics) , correlation coefficient , econometrics , medicine , engineering , physical therapy , psychometrics , geometry , systems engineering
SUMMARY The design of family studies to estimate the value of an intraclass correlation coefficient p is considered when n i individuals are to be selected from each of k families, i = 1, 2, …, k. In particular, the accuracy of a balanced design ( n i = n , i = 1,2,…, k ) for estimating p is compared with the accuracy of an unbalanced ‘natural’ design, in which the n i are sampled at random from family size distributions that tend to occur in practice. It is found for two different estimators of p that the balanced design is usually preferable, but only to a small degree if the number of families sampled is greater than 50.