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Assignment of the gene for cytosolic alanine aminotransferase (AAT1) to human chromosome 8
Author(s) -
ASTRIN K. H.,
ARREDONDOVEGA F. X.,
DESNICK R. J.,
SMITH M.
Publication year - 1982
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1111/j.1469-1809.1982.tb00703.x
Subject(s) - cytosol , gene , alanine aminotransferase , alanine , chromosome , genetics , biology , chemistry , microbiology and biotechnology , biochemistry , enzyme , endocrinology , amino acid
SUMMARY The segregation of human cytosolic alanine aminotransferase (AAT1) and the individual human chromosomes has been studied in 27 secondary and tertiary rat hepatoma‐human (liver) fibroblast hybrids. The staining solution used to visualize AAT activity on starch gels was specific for AAT since it was visualized only when all components of the stain were present. The locus for human AAT1 has been assigned to chromosome 8.