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Linkage between dentinogenesis imperfecta and Gc
Author(s) -
BALL S. P.,
COOK P. J. L.,
MARS M.,
BUCKTON K. E.
Publication year - 1982
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1111/j.1469-1809.1982.tb00693.x
Subject(s) - dentinogenesis imperfecta , recombination fraction , locus (genetics) , lod score , genetics , dentinogenesis , genetic linkage , recombination , biology , osteogenesis imperfecta , medicine , chromosome , gene , dentistry , gene mapping , anatomy , odontoblast , dentin
SUMMARY A large family with dentinogenesis imperfecta shows that this locus is linked to the Gc locus on chromosome 4q. The maximum lod score is + 7.9 at a male recombination fraction of 0.05 and female recombination fraction of 0.24.