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The effect of social selection on the population dynamics of Huntington's disease
Author(s) -
YOKOYAMA SHOZO,
TEMPLETON ALAN
Publication year - 1980
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1111/j.1469-1809.1980.tb01574.x
Subject(s) - huntington's disease , selection (genetic algorithm) , disease , population , dynamics (music) , biology , evolutionary biology , demography , psychology , medicine , computer science , sociology , artificial intelligence , pedagogy
Summary Wallace (1976) postulated the importance of social selection on the frequency of Huntington's disease. This effect of social selection was studied with respect to the population dynamics of Huntington's disease genes. It is shown that social selection operates mainly through heterozygotes. Existing data indicate that the frequency of Huntington's disease in the population is determined by its social effects.