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The applicability of the Hardy‐Weinberg principle in the study of populations
Author(s) -
SCHAAP T.
Publication year - 1980
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1111/j.1469-1809.1980.tb00960.x
Subject(s) - hardy–weinberg principle , genotype frequency , population , genotype , statistical physics , allele frequency , biology , physics , genetics , demography , sociology , gene
Summary The applicability of the Hardy‐Weinberg principle in the analysis of a theoretical population under directional selection is assessed. It can be shown that the analysis of genotype frequencies by the conventional method can never reveal the existence of directional forces. Consequently, a population actually in transient polymorphism may seem to be either in Hardy‐Weinberg equilibrium or subject to balancing or disruptive forces. Therefore, population studies should not be based on genotype frequencies at a single point in time.