Premium
The genotypic distribution of relatives of homozygotes when consanguinity is present
Author(s) -
ELSTON R. C.,
LANGE K.
Publication year - 1976
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1111/j.1469-1809.1976.tb00157.x
Subject(s) - biostatistics , chapel , library science , annals , demography , genealogy , geography , history , medicine , sociology , classics , computer science , epidemiology , art history
A correction is made to an expression given by Jacquard (1968, 1972a,b) for the genotypic distribution of a relative of a given homozygote when consanguinity is present. The correction will necessarily be small either if the allele present in the given homozygote has a frequency of near unity, or if the coefficient of inbreeding of the given homozygote is small.