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The genetics of the Lp Antigen
Author(s) -
SING C. F.,
SCHULTZ JANE S.,
SHREFFLER D. C.
Publication year - 1974
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1111/j.1469-1809.1974.tb01992.x
Subject(s) - genetics , locus (genetics) , inheritance (genetic algorithm) , biology , antigen , evolutionary biology , gene
SUMMARY Several genetic models were considered to explain the distribution of qualitatively positive and negative children in 204 Caucasian families. A model which best describes the inheritance of the Lp antigenic expression involves a major genetic locus which distinguishes two overlapping continuously distributed modes of quantitative activity.