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Distribution of genetic variants of erythrocyte phosphoglycerate kinase (PGK) and phosphohexose isomerase (PHI) among some population groups in south‐east Asia and Oceania
Author(s) -
OMOTO K.,
BLAKE N. M.
Publication year - 1972
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1111/j.1469-1809.1972.tb00581.x
Subject(s) - glucose 6 phosphate isomerase , phosphoglycerate kinase , new guinea , population , biology , geography , gene , genetics , demography , ethnology , history , enzyme , biochemistry , sociology
SUMMARY More than 4000 blood samples from populations in Japan, Micronesia, Singapore, West Irian, New Guinea and Australia have ben typed for phosphoglycerate kinase (PGK) and phosphohexose isomerase (PHI) Normal PGK‐1 patterns were observed in all populations except in Micronesia, parts of West Irian and the Western and Eastern Highlands of New Guinea. In Micronesia both PGK‐2 and PGK2‐1 patterns were observed and the gene frequency of pgk 2 was 0.07. In West Irian and the Highlands of New Guinea PGK‐4 and PGK 4‐1 patterns were observed and the highest pgk 4 frequency was 0.051 among males in the Western Highlands. Only nine individuals were detected with PHI variant patterns. One PHI 2‐1 was found in a Chinese and two PHI 3‐1 persons were observed among Malays in Singapore, four PHI 5‐1 in the Western Highlands of New Guinesa and one PHI 5‐1 in a Japanese: one PHI 4‐1 was found among Aborigines in Northern Australia.