Premium
The analysis of X‐linkage
Author(s) -
EDWARDS J. H.
Publication year - 1971
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1111/j.1469-1809.1971.tb00237.x
Subject(s) - linkage (software) , recombination fraction , genetics , genetic linkage , interpretation (philosophy) , simple (philosophy) , chromosome , recombination , biology , fraction (chemistry) , mathematics , statistics , computer science , gene mapping , chemistry , gene , chromatography , philosophy , epistemology , programming language
SUMMARY The estimation of the recombination fraction between pairs of loci on the X‐chromosome is discussed, with special reference to the bias from defined forms of ascertainment. Tables are presented which give lods corrected for the common forms of ascertainment. The interpretation of lods is discussed, and the concept of equivalent observations introduced. A simple counting system is described for use in close linkage.