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Short‐arm deletion, chromosome 4, (4p‐), a syndrome?
Author(s) -
TAYLOR A. I.,
CHALLACOMBE D. N.,
HOWLETT R. M.
Publication year - 1970
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1111/j.1469-1809.1970.tb00227.x
Subject(s) - trisomy , chromosome , genetics , long arm , chromosome 21 , down syndrome , biology , arc (geometry) , chromosome 4 , gene , mathematics , geometry
SUMMARY Two cases of new‐born infants with severe multiple congenital anomalies of the ‘mid‐line’ type and a 4 p – deleted chromosome arc presented. Clinieal and other findings are compared with 8 published cases and with findings in Edwards' syndrome (18 trisomy), Patau's syndrome (13 trisomy) and cri du chat syndrome (5 p –). The identification of the deleted chromosome by autoradiography and measurements is discussed.