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Differences between families in the amount of salivary H substances *
Author(s) -
PLATO CHRIS C.,
GERSHOWITZ HENRY
Publication year - 1962
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1111/j.1469-1809.1962.tb01308.x
Subject(s) - abo blood group system , saliva , mating type , biology , mating , genetics , physiology , immunology , biochemistry , gene
Summary The saliva ABO inhibition titres of the members of twenty‐eight 0X0 and ten BxO mating types were determined. The results of the examinations suggest that: (1) A precursor ‘H’ substance is formed by all secretors which is converted into A, B, or AB depending on the individual's blood group. (2) the titres of the H substance secreted by members of the same sibship and of the same blood group are very uniform (high intra‐class correlation) indicating genetic control over the amount of the soluble ABO substances secreted. A genetic hypothesis was put forward to account for these findings.