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THE RATE OF APPROACH TO HOMOZYGOSITY
Author(s) -
MORAN P. A. P.
Publication year - 1958
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1111/j.1469-1809.1958.tb01436.x
Subject(s) - wright , population , term (time) , mathematics , mutation , expression (computer science) , computer science , genetics , biology , physics , demography , quantum mechanics , sociology , gene , programming language
Summary In Wright's model of a finite population without mutation, the leading term in the expression for the probability that the population is homozygous was obtained approximately by Wright. Kimura obtained a full and exact solution to the corresponding approximating diffusion model. For a new model involving overlapping generations the leading terms in the expansion of the probability can be obtained exactly and these are compared with the corresponding approximation of Kimura type.