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MUSCULAR DYSTROPHY IN NORTHERN IRELAND
Author(s) -
STEVENSON A. C.,
CHEESEMAN E. A.,
HUTH MARY CLARE
Publication year - 1955
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1111/j.1469-1809.1955.tb01341.x
Subject(s) - linkage (software) , genetics , genetic linkage , abo blood group system , biology , gene
Summary Sib pairs from twenty‐six Northern Ireland families with at least one member affected by ‘autosomal limb‐girdle muscular dystrophy’ have been examined for linkage between the dystrophy and sex, colour vision, taste sensitivity to phenylthiocarbamide, ABO , Rhesus, Lewis ( a ), P, MNS and salivary secretion of AB antigens. The data present no definite signs of linkage; the only significant score obtained by Penrose's sib‐pair method was for Lewis ( a ) in 128 sib pairs from families in which affected members had no face involvement. In view of the small amount of information available in this isolated instance and the relatively large number of tests made, the evidence for linkage with Lewis ( a ) in this group of families is unconvincing.