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The role of oxygen‐associated therapies for the healing of chronic wounds, particularly in patients with diabetes
Author(s) -
Brimson C.H.,
Nigam Y.
Publication year - 2013
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.2012.04650.x
Subject(s) - medicine , hyperbaric oxygen , wound healing , oxygen delivery , intensive care medicine , chronic wound , diabetes mellitus , psychological intervention , oxygen , surgery , nursing , chemistry , organic chemistry , endocrinology
This paper discusses the role of molecular oxygen as an aid to wound healing, and the potential value of the three major therapies which allow the delivery of oxygen to the wound site: Hyperbaric Oxygen Therapy (HBOT), Topical Oxygen Therapy (TOT) and a new sterile wound dressing, Oxyzyme TM . We summarize studies which have been undertaken using these interventions, and discuss their reported effect on chronic, non‐healing wounds, in particular, on ulcers associated with Diabetes. The main conclusions drawn from the studies reviewed indicate that therapeutic oxygen can be used as an aid to the healing of chronic wounds; and benefits are clearly evident with the use of both HBOT and TOT. There is also potential for the use of a new, portable, topical oxygen delivery system, oxyzyme. However its use is still embryonic and studies on its effectiveness are limited. More robust measures of its efficacy are urgently needed.