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Natural options for the management of hyperpigmentation
Author(s) -
Leyden J.J.,
Shergill B.,
Micali G.,
Downie J.,
Wallo W.
Publication year - 2011
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.2011.04130.x
Subject(s) - medicine , kojic acid , depigmentation , dermatology , hyperpigmentation , arbutin , topical agents , cosmetics , traditional medicine , population , cosmeceutical , tyrosinase , pathology , biochemistry , chemistry , environmental health , enzyme
Facial hyperpigmented disorders are a common complaint in the adult population of all races. First‐line topical treatments are usually hydroquinone or topical retinoids, which can cause irritant reactions. The need for better tolerated, yet effective, skin lightening agents that could be utilized by a wider population has led to the investigation of several potential botanical/natural compounds. There are currently many topical cosmetic formulations claiming skin depigmenting effects. A few of the ingredients (e.g. soy) are supported not only by in vitro results but also by a body of controlled clinical efficacy studies; other ingredients, instead, are backed mostly by in vitro data and a few small uncontrolled clinical studies. In this review, we describe the most common natural ingredients used for skin depigmentation and their major published studies: soy, licorice extracts, kojic acid, arbutin, niacinamide, N‐acetylglucosamine, COFFEEBERRY ™ and green tea.