Premium
Subcutaneous Rosai–Dorfman disease: is surgical excision justified?
Author(s) -
Cheng SP,
Jeng KS,
Liu CL
Publication year - 2005
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.2005.01297.x
Subject(s) - medicine , rosai–dorfman disease , disease , surgical excision , surgery , pilonidal disease , natural history , surgical resection , pathology
Rosai–Dorfman disease in soft tissue without nodal disease has been recognized as a distinct clinicopathologic entity. It may represent a diagnostic challenge and the natural history and optimal treatment has not been well clarified. We investigated a patient in whom Rosai–Dorfman disease was confined to the subcutis of the abdominal wall and recurred after incomplete excision. Complete resolution was achieved by wide surgical excision with negative margins. Pathologic examination confirmed the diagnosis of extranodal Rosai–Dorfman disease. The patient is disease‐free after 1 year of follow‐up. Despite the possibility that spontaneous remission may occur, our results suggest that when anatomically feasible, complete excision can be a treatment option for persistence or recurrence of exclusively extranodal disease. Larger case series and longer follow‐up are needed to assess the long‐term efficacy in these patients.