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Dermal fibrosis and cutaneous necrosis after recombinant interferon‐β1a injection in a multiple sclerosis patient
Author(s) -
Ozden MG,
Erel A,
Erdem O,
Oztas MO
Publication year - 2005
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.2004.01086.x
Subject(s) - medicine , myalgia , multiple sclerosis , interferon , recombinant dna , necrosis , dermatology , intramuscular injection , fibrosis , injection site , immunology , pathology , biochemistry , chemistry , gene
The most commonly reported side‐effects of recombinant interferon‐β1a and 1b include local inflammatory injection site reactions, headache, fever, myalgia and a flu‐like syndrome. In this case report, we describe the occurrence of cutaneous necrosis and dermal fibrosis following intramuscular interferon‐β1a injections in a multiple sclerosis patient.