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Oral isotretinoin and haemophilia A
Author(s) -
Bettoli V,
Pizzigoni S,
Vasina S,
Mancino A,
Virgili A
Publication year - 2004
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.2004.01062.x
Subject(s) - medicine , isotretinoin , acne , dermatology , thrombocytosis , haemophilia , haemophilia a , fibrinolysis , coagulation , pediatrics , platelet
The effects of oral isotretinoin on the coagulation system are still not well known: some case reports describe thrombocytopenia or thrombocytosis, others present different effects on fibrinolysis. We report a case of severe acne treated with oral isotretinoin in a patient affected with haemophilia A. In this case, which differs from the only other case reported in the literature, oral isotretinoin did not appear to influence the haemophilic patient's need of factor VIII.