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Erythema multiforme during cytomegalovirus infection and oral therapy with terbinafine: a virus–drug interaction
Author(s) -
Carducci M,
Latini A,
Acierno F,
Amantea A,
Capitanio B,
Santucci B
Publication year - 2004
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.2004.00806.x
Subject(s) - medicine , erythema multiforme , terbinafine , serology , dermatology , cytomegalovirus , erythema , drug , anti nuclear antibody , adverse drug reaction , immunology , virus , virology , antibody , viral disease , herpesviridae , pharmacology , itraconazole , antifungal , autoantibody
The authors report a case of erythema multiforme in a 32‐year‐old woman who was also taking oral terbinafine for an onychomycosis. The patient data analysis showed serological positivity for cytomegalovirus (IgM and IgG) and hepatitis C virus and serological titre of antinuclear antibody was elevated. After a brief review of the literature the authors propose the possibility of virus–drug interaction as a model of adverse drug reactions.