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Multinucleate cell angiohistiocytoma: a report of two cases
Author(s) -
Aloi F.,
Solaroli C.,
Tomasini C.,
Pippione M.
Publication year - 1998
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.1998.tb00954.x
Subject(s) - multinucleate , giant cell , medicine , reticular connective tissue , reticular dermis , pathology , stroma , dermis , anatomy , pathological , immunohistochemistry
We report the clinical, histological and immunological features of two cases of multinucleate cell angiohistiocytoma (MCAH) in women of 32 and 53 years of age, respectively. Clinically, MCAH occurs mostly in middle‐aged women and consists of crops of reddish‐purple, dome‐shaped papules especially on the limbs. Histologically, the reticular dermis presents an increased number of small vascular channels with plump endothelial cells embedded in a fibrohistiocitic stroma with numerous bizarre multinucleate cells. Bizarre multinucleated cells are not specific to MCAH; they can be observed in numerous other cutaneous conditions. However, MCAH presents quite distinctive clinico‐pathological findings and may be easily differentiated from other cutaneous disorders.