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Efficacy of cyclosporine plus etretinate in the treatment of erythrodermie psoriasis (three case reports)
Author(s) -
Kokelj Franco,
Plozzer Carmela,
Torsello Pierpaolo,
Trevisan Giusto
Publication year - 1998
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.1998.tb00776.x
Subject(s) - etretinate , medicine , psoriasis , dermatology , regimen , acitretin , incidence (geometry) , surgery , physics , optics
Background Association of different treatments are often used in erythrodermic psoriasis in order to increase the effectiveness and decrease the incidence of side effects due to single drugs. Materials and methods Three in‐patients affected by erythrodermic psoriasis, not responding to cyclosporine, (two patients) and etretinate, (one patient), were treated with the association cyclosporine plus etretinate. Results Clinical response was prompt to the combined therapy. The two drugs were tapering off gradually over 6 months; the patients maintained the remission for prolonged period. Conclusions Combined cyclosporine‐etretinate therapy may be considered as an effective and well tolerated treatment of erythrodermic psoriasis in patients not responding to monotherapy regimen.