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The pathogenesis of lipodermatosclerosis: facts, uncertainties and theories
Author(s) -
Naschilz Jochanan E.,
Yeshurun Daniel,
Misselevich Ines,
Boss Jochanan H.
Publication year - 1997
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.1997.tb00504.x
Subject(s) - medicine , chronic venous insufficiency , eosinophilic fasciitis , pathogenesis , fasciitis , pathological , dermatology , surgery , pathology
Lipodermatosclerosis is the accepted term for describing induration of the skin and subcutaneous layers of the legs in patients with venous insufficiency. The pathogenic processes leading from venous insufficiency to lipodermatosclerosis are poorly understood. Based on their clinico‐pathological studies of different subcutaneous indurative disorders, the authors suggest that lipodermatosclerosis exhibits similarities to eosinophilic fasciitis and other fasciitis panniculus syndromes. The theories of the pathogenesis of lipodermatosclerosis are reviewed and a unifying pathogenetic concept is proposed. The lipodermatosclerosis is best conceived as fasciitis paniculata reaction evolving in the calf of the patient with venous insufficiency.