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The plasma level of sICAM‐1 in the chosen inflammatory dermatoses
Author(s) -
LecewiczToruń Barbara,
Krasowska Dorota,
Kozioł Maria,
Chodorowska Grażyna
Publication year - 1997
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.1997.tb00453.x
Subject(s) - mycosis fungoides , psoriasis , medicine , dermatology , plasma levels , gastroenterology , immunology , lymphoma
We have determined the plasma levels of sICAM‐l in 11 patients with generalized lichen planus, 19 with psoriasis, 10 with acrosderoderma. 4 with mycosis fungoides and 14 patients of the control group. All the investigated groups displayed mean values significantly higher than those of the controls (199.5 ± 97.7 ng/ml), and values in generalized lichen planus subjects were much higher (426.8 ± 145.5 ng/ml) than in those with acrosderoderma (360.8 ± 121.7 ng/ml), psoriasis (356.9 ± 175.6 ng/ml) and mycosis fungoides (329.4 ± 142.3 ng/ml). These data suggest that the level of sICAM‐l in plasma increases during different immunological skin diseases. Soluble ICAM‐I is a sensitive marker of inflammatory states in the course of the investigated diseases.