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Chronic urticaria associated with autoreactivity to progesterone
Author(s) -
Sousa Pinto J.M.,
Campos Luis B.,
Ascensão A. Cabral
Publication year - 1997
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.1997.tb00261.x
Subject(s) - medicine , exacerbation , luteal phase , dermatology , hormone
Autoimmune progesterone dermatitis is a rarely recognized cutaneous disorder revealed by recurrent and cyclic skin eruption with variable morphology, during the luteal phase. We report the case of a 42‐year‐old woman with chronic urticaria since the age of 38 with premenstrual exacerbation. Intradermal progesterone tests revealed a strong reactivity against this hormone. Treatment with thalidomide was effective but induced a peripheral neuropathy. Oophorectomy was performed with clearing of the cutaneous lesions.