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Photodynamic therapy of superficial basal cell carcinomas using exogenous 5‐aminolevulinic acid and 514‐nm light
Author(s) -
Alvanopoulos Kosmas,
Antoniou Christina,
Melpo Petrou,
Vareltzidis Antonis,
Katsambas Andreas
Publication year - 1997
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.1997.tb00251.x
Subject(s) - photodynamic therapy , medicine , basal cell carcinoma , dermatology , basal cell , red light , melanoma , laser therapy , actinic keratoses , pathology , laser , cancer research , optics , chemistry , botany , physics , organic chemistry , biology
Objective The evaluation of the effectiveness of topical photodynamic therapy with 5‐aminolevulinic acid (5‐ALA) and green laser light on superficial basal cell carcinomas. Background Topical photodynamic therapy with exogenous 5‐ALA and visible or red laser light has been used up to now for the treatment of superficial non‐melanoma skin tumors. Patients and methods Four patients with nine superficial carcinomas participated in this study. The tumors were irradiated with green laser light 5 h after the application of cold cream with 20% aminolevulinic acid under occlusive dressing. Results All nine lesions were resolved with a single treatment and clinical evidence of recurrence was observed in one tumor 1 year after the therapy. Conclusion Topical photodynamic therapy with exogenous 5‐ALA and green laser light is very effective for superficial basal cell carcinomas.