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Comparative effects of two different calcipotriol (MC 903) cream formulations versus placebo in psoriasis vulgaris. A Randomised, Double‐Blind, Placebo‐Controlled, Parallel Group Multi‐Centre Study 1
Author(s) -
Harrington Christine I.,
Goldin David,
Lovell Christopher R.,
Kerkhof Peter,
Nieboer Cees,
Austad Joar,
Molin Lars,
Clareus Birgitta Wilson,
RaskPedersen Eva
Publication year - 1996
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.1996.tb00159.x
Subject(s) - calcipotriol , medicine , psoriasis , placebo , dermatology , double blind , placebo group , double blind study , pathology , alternative medicine
Background Calcipotriol ointment is an effective treatment For psoriasis vulgaris. Although cream formulations have a less emollient effect they are often more acceptable to patients. Objective To compare calcipotriol 50 μg/g in two different cream formulations with vehicle in patients with psoriasis vulgaris. Method A randomised, double‐blind, parallel group, multi‐centre, comparison of cream A in which calcipotriol 50μg/g is dissolved, cream B in which calcipotriol 50 μg/g is suspended as tine particles and vehicle. A 2‐week wash‐out period was followed by 8 weeks double‐blind treatment.