Premium
Coexistence of rheumatoid arthritis, myasthenia gravis, and pemphigus superficialis ⋆
Author(s) -
Schiavo Ada,
Guerrera Vincenzo,
Migliaresi Sergio,
Lombardi Maria Luisa,
Ruocco Vincenzo
Publication year - 1995
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.1995.tb00544.x
Subject(s) - medicine , rheumatoid arthritis , myasthenia gravis , pemphigus , pemphigus foliaceus , pemphigus vulgaris , thymectomy , immunology , dermatology , penicillamine , thymoma , autoantibody , antibody
d ‐Penicillamine (DP) is widely used nowadays in the treatment of rheumatoid arthritis, despite its well known side effects of an autoimmune nature, often associated with specific histocompatibility antigens (HLA). We report the case of a woman, suffering from rheumatoid arthritis (RA), treated with DP, who developed myasthenia gravis (MG) and pemphigus foliaceus (PF) and whose phenotype has only antigens usually associated with pemphigus. This may he the second published case of concurrent pemphigus and myasthenia gravis induced by d ‐penicillamine therapy, in the absence of thymoma.