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Atypical herpes zoster in a patient with AIDS
Author(s) -
FernándezDíaz M.L.,
Herranz P.,
Lucas R.,
GonzálezGarcía J.,
SuárezMarrero M.C.,
Contreras F.,
Casado M.
Publication year - 1995
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.1995.tb00439.x
Subject(s) - medicine , foscarnet , virus , aciclovir , antiviral therapy , virology , viral load , herpes virus , human immunodeficiency virus (hiv) , dermatology , viral disease , immunology , herpesviridae , chronic hepatitis
Objective To report a case of persistent infection by varicella‐zoster virus (VZV) in an HIV‐infected patient who presented with atypical, hyperkeratotic viral lesions and a partial response to acyclovir. Methods Viral changes found on histopathological examination; definitive diagnosis of VZV infection was established by viral culture. Results Lesions of chronic hyperkeratotic herpes zoster responded partially to acyclovir therapy, and complete resolution was achieved with intravenous foscarnet. Absence of visceral involvement. Conclusion Prolonged acyclovir therapy for herpes virus infections in HIV‐seropositive patients may represent an important pathogenic factor for the appearance of atypical clinical forms associated with drug‐resistant viral strains.