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White sponge nevus. Seven cases in the same family
Author(s) -
RodriguezSerna Mercedes,
Pérez Amparo,
Febrer Isabel,
BotellaEstrada Rafael,
Aliaga Adolfo
Publication year - 1995
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.1995.tb00352.x
Subject(s) - medicine , oral mucosa , asymptomatic , dermatology , histology , nevus , differential diagnosis , white (mutation) , sponge , pathology , melanoma , biochemistry , chemistry , botany , cancer research , biology , gene
Seven cases of white sponge nevus in seven women of the same family are reported. At birth the patients had lesions consisting of asymptomatic white spongy plaques located on the oral mucosa; in two patients the lesions also involved the vaginal mucosa. The lesions improved after antibiotic treatment. Histology was performed in four cases and an ultrastructural study in one. The findings were consistent with the diagnosis of white sponge nevus in all cases. Differential diagnosis was made with other conditions presenting as white lesions of the oral mucosa.