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Skin disorders and Epstein Barr virus primary infection: results of a 31 month survey
Author(s) -
Baldari Urbano,
Cancellieri Claudio,
Celli Barbara,
Zanelli Rossella,
Raccagni Antonio Ascari
Publication year - 1995
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.1995.tb00345.x
Subject(s) - medicine , erythema multiforme , dermatology , erythema nodosum , seroconversion , serology , erythema , epstein–barr virus , immunology , virus , pathology , antibody , disease
Objectives To investigate skin disorders related to Epstein Barr Virus (EBV) seroconversion and review the literature on this topic. Patients and methods 77 patients admitted to three Departments (Dermatology, Infectious Diseases, Pediatrics) presented clinical and laboratory (Enzyme Linked Immunosorbent Assay) findings of EBV primary infection. 54/77 (70.1%), ranging in age from 9 months to 41 years and suffering from various skin disorders, were selected. Results 8/54 presented Infantile papular acrodermatitis (Gianotti‐Crosti syndrome); 42/54 exanthema, 2/54 acute urticaria, 1/54 erythema multiforme, 1/54 erythema nodosum. Conclusion After reviewing the available literature on the subject and in the light of these findings, it is possible to assert that EBV‐primary infection is not infrequently associated with skin symptoms. Clinicians may sometimes understimate the problem, and it would be useful to include EBV serology among the tests for the diagnosis of reactive cutaneous diseases occurring in subjects under 3D years old.