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CA15‐3(DF3) antibody reacts to normal sweat and sebaceous glands
Author(s) -
Ando Iwao,
Yasui Shoko,
Kukita Atsushi,
Hino Haruko
Publication year - 1994
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.1994.tb00375.x
Subject(s) - sweat gland , sweat , medicine , monoclonal antibody , antigen , pathology , antibody , immunohistochemistry , immunology
Aim To study the localization of CA15‐3 antigen in normal skin. Background CA15‐3 antigen can be useful in the investigation of skin appendages. Methods Specimens of paraffin embedded normal skin were stained by CA15‐3(DF3) monoclonal antibody. Results Sebaceous glands and secretory segments of sweat glands were strongly positive. Conclusions Skin appendages express CA15‐3 antigen in common with other epithelial gland tissues. This antigen is especially useful as a marker of the secretory segment of sweat glands.